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Lipoedema is a disorder characterized by an excessive accumulation of subcutaneous body fat, characterized by pain or soreness as well as accumulation of fat deposits, particularly in the extremities. The onset of lipoedema often occurs at times of female hormonal change such as puberty, during pregnancy, perimenopause or menopause. The pathophysiology of the pain is not fully understood, but increased inflammation, compression of peripheral nerves by proliferating adipose tissue, and fluid accumulation in the area occupied by lipedema have been implicated as possible causes. |
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But, what we do know:
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